Not So FAST- Chest Ultrasound Underdiagnoses Traumatic Pneumothorax

Jarrett E. Santorelli J, Chau H, Godat L, et al. J Trauma Acute Care Surg 92:44-48, 2022 DOI: 10.1097/TA.0000000000003429.

Background Gold standard for diagnosis of pneumothorax in people is computed tomography (CT). Initial reports suggest high sensitivity of ultrasound (US) for detection of pneumothorax.
Rational and Objective The hypothesis was US would be more sensitive than supine (ventrodorsal) chest x-ray for detection of pneumothorax
Trial Design Retrospective study
Patient population and location Level 1 trauma center 2018-2020
Methods
  • Chest x-ray and US done prior to intervention or CT
  • Trained registered sonographer
  • Real time evaluation and immediate evaluation by radiologist
  • Immediate tube thoracostomy defined as need for chest tube within 8 hours of admission
Endpoints (if applicable) n/a
Results
  • 568 patients diagnosed with pneumothorax, 363 met study criteria
  • 191 occult – small air pockets/blebs on CT – excluded from subsequent analysis
  • 87% blunt trauma, 13% penetrating trauma
  • Sensitivity of x-ray 43%, sensitivity of US 35% in 363 patients
  • Removal of occult pneumothorax:
    • x-ray sensitivity 78% – false negative 22% 
    • US sensitivity 65% – false negative 36%
      • 50% false negative needed chest tube, 85% immediately
  • First study with findings suggesting x-ray better than US
  • Many tubes placed after repeat chest x-ray (at 1 to 6 hours)
Limitations
  • Single centre, retrospective study
  • Selection bias possible
  • False positives not included as not identified in this study
  • Follow-up examinations not done so pneumothorax may have developed in some patients that were not identified in the medical record  
Clinical Relevance Conclusions
  • Caution when using US to positively diagnose significant pneumothorax
  • Maintain high level of suspicion; repeat exams and imaging are important
  • More studies needed in veterinary medicine to determine if similar findings especially as lateral view used more commonly than ventrodorsal